12 months after stem cell therapy for knee AVN, the individual is performing very well. This patient noted diminished pain, improved function and walking. Overall a much better total well being was reported.


Knee pain is a very common orthopaedic problem. Avascular necrosis (AVN) takes place when the blood circulation into a region of bone becomes impaired. This lack of blood flow results in ischemia ultimately causing bone cell death or necrosis. This is commonly called avascular necrosis (AVN), though a number of other names happen to be accustomed to describe exactly the same condition.

AVN may be also called osteonecrosis, ischemic necrosis, aseptic necrosis and bone infarction.

AVN is mostly observed in the hip, then the shoulder, then your knee joint. AVN may be seen in one joint or multiple joints based upon associated or causative factors. The hip is the most common joint to be seen bilateral or in both hips. It may also present as hip and knee involvement, or multiple other joints.

Trauma is the leading cause of knee AVN. Another leading source of AVN is idiopathic or unknown etiologies. Other associated or causative factors include excessive corticosteroids (cortisone), autoimmune disorders (Lupus or Rheumatoid Arthritis), radiotherapy, chemotherapy, excessive alcohol use, sickle cell disease, decompression sickness, coagulation disorders, Vasculitis, lipid storage disease, and AIDS.

Traumatic AVN could possibly be seen shortly after an injury, however diagnosis might be delayed just like trauma pain occurs plus it not immediately suspected until healing does not occur quickly. If AVN is not promptly evaluated or even the section of necrosis is large, the harder chance of the necrotic area of bone may collapse bringing about rapid joint degeneration. This secondary degeneration is regarded as the feared complication from the initial diagnosing AVN.

The rationale for ischemic necrosis is usually to retard secondary degeneration or promote a healing cascade via a various mechanisms.

People are also seeking stem cell therapy in cases of knee AVN instead of knee joint replacement surgery. The truth is stem cell care is learning to be a more frequent request for patients which avoid all knee surgery, or who have not found the success they demand after already having had knee surgery. These people are opting for knee stem cell treatment instead.
The opportunity of diminished knee pain, improvement in function, walking, way of life or sports participation all are part of the equation in factoring knee stem cell options.

The possibility of avoiding knee replacement surgery is an incredibly frequent consideration, specifically patients with knee AVN.

If your in pain or had an injury and therefore are looking for an alternative to surgery, e mail us immediately at our locations. Our Main Medical Center located in Tampa Bay, Florida (727) 462-5582 or at Beverly Hills, California (310) 975-7033.
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